(2S)-1-[(1S)-1-[BIS(2-METHYLPHENYL)PHOSPHINO]ETHYL]-2-(DI-2-FURANYLPHOSPHINO)FERROCENE is a chiral organic compound. The following is an introduction to its nature, use, preparation and safety information:
Nature:
-Appearance: Colorless or light yellow solid.
-Melting point: about 180-190 ℃.
-Solubility: Soluble in some common organic solvents.
Use:
-Catalyst: This compound is a chiral ligand, widely used in metal-catalyzed reactions. It exhibits high catalytic activity and selectivity in asymmetric catalytic reactions, including asymmetric hydrogenation, reduction, asymmetric cyclization and asymmetric carbonylation.
Preparation Method:
-A commonly used preparation method is to synthesize through a two-step reaction: first, (2-furyl) phosphine chloride and (dimethyl sulfoxide) ferrocenyldiethylphosphine bromide are reacted with dimethyl sulfoxide to generate (RP)-2-[di (2-furyl) phosphino] ferrocenyl compound; then, reaction with bis (dimethylaminoethyl) diphenylphosphine under basic conditions yields the final target compound.
Safety Information:
-This compound has limited safety information, but it is generally believed to have low toxicity to the human body.
-Nevertheless, any chemical should be handled with caution and in accordance with appropriate laboratory practices and safe operating procedures.
-When using and handling this compound, care should be taken to avoid contact with skin and eyes and maintain good ventilation.